EDGE TECHNOLOGIES FOR SINGLE CELL GENOMICS
Capture precious samples anywhere — even at clinical network edges
Lock-in biological states and store as long as needed
Process centrally for better efficiencies and reduced variability
cell drives
Genomic resolution at the individual cell level is powering the next phase of precision health. Honeycomb offers a new paradigm in single-cell technology—cell drives for the collection and storage of biological samples for asynchronous single-cell analysis. Founded on pioneering nanowell technology from MIT, our HIVE Cell Drives enable scalable and cost-effective single-cell interrogation of samples, with the efficiency and quality of centralized analytical processing. Honeycomb aims to expand single-cell opportunities in discovery, diagnostics, and monitoring to clinical settings throughout the world.
Capture
Cellular expression changes rapidly, so we lock signal at point and time of collection.
Honeycomb devices require no complex equipment or training, so samples can be can be collected in almost any setting.
Gentle stabilization process allows even the most fragile cells to be captured.
storage
Cellular expression changes rapidly, so we lock signal at point and time of collection.
Honeycomb devices require no complex equipment or training, so samples can be collected in almost any setting.
Gentle stabilization process allows even the most fragile cells to be captured.
Centralized Processing
Honeycomb single-cell devices enable samples to be processed centrally, which improves efficiencies and reduces variabilities.
While Honeycomb does not rely on a complex processing instrument, our devices are designed to work with all major automated liquid handling workflows.
Honeycomb’s open array format allows for a variety of profiling applications, beyond just single-cell RNAseq.
Use Cases
Distributed collection
HIVE drives are ideal for collecting samples in multi-center clinical studies.
Fragile cell types
Honeycomb’s array-based cell isolation format has successfully been used to capture even the most delicate or labile types of cells (granulocytes, nephrons, hepatocytes, and neurons)
Sparse samples
Precious samples containing only a few thousand cells — or even a few hundred — can be successfully profiled with Honeycomb’s HIVE drives.
Founded by world leaders
in single-cell technology
Jim Flanigon, PhD, MBA
Chief Executive Officer
Life science and technology executive. Expertise in genomics, molecular diagnostics, and precision medicine, including roles at Genzyme, CCE, and Oracle.
Todd Gierahn, PhD
Chief Science Officer
Single-cell and immunology pioneer. MIT senior researcher on single-cell technologies. Developed foundational platform for Genocea Biosciences.
Brian Hutchison, PhD
Sr. VP Development & Ops
Life science operations executive. Genomic development and operations leader at Qiagen and Rain Dance.
Alex K. Shalek, PhD
massachusetts institute of technology
Pfizer-Laubach Career Development Assistant Professor, IMES and Chemistry at MIT. Leader in the development of new technologies for deep, integrated molecular profiling of cells and their interactions.
J. Christopher Love, PhD
massachusetts institute of technology
Professor of Chemical Engineering at Koch Institute for Integrative Cancer Research at MIT. Focus on technologies that address biological questions in immunology, microbiology, systems biology, and bioprocess engineering.