See All Your Cells
Recover complete biological information from your sample, even from fragile or delicate cells
Cells isolated using the HIVE settle gently into microwells, avoiding elevated pressures or microfluidic shear forces common in other methods.
A researcher has been attempting to recover neutrophils from whole blood clinical samples. He has been struggling to recover neutrophils with current microfluidic platforms in the lab, but the HIVE’s gentle capture of cells enables him to generate data for neutrophils and other fragile cell types.
Any where, Any time
Capture cells wherever and whenever they are available without compromising data quality
The upper plots show the complete recovery of all cell types from HIVEs processed on Day 0 (fresh) or Day 14 (stored at -20C). The bar plot shows that the relative frequency of each cell type is consistent between these timepoints.
A clinical researcher receives bone marrow biopsies at odd hours, making it challenging to process them fresh and at the same time for ideal data quality. Additionally, the specialized equipment required for her current single cell solution is not always available. With the HIVE, she can capture her samples at any time, then store her cell-loaded HIVE(s) until all samples are ready for processing together, as if they had been processed fresh.
Flexible Sample Handling
Run one or many samples in parallel, in a wide range of volumes
The HIVE workflow accommodates a broad range of sample numbers and volumes.
Minimal impact in overall time and user experience running anywhere from 1 to 24 samples in parallel. From single cells to NGS libraries only takes 1.5 hours longer for 24 HIVEs vs. 1 HIVE.
Limited constraints on sample loading volume. Load between 1 and 4 mLs per HIVE. Top up samples < 1 mL with sample buffer or sequentially load samples > 4 mL.